Control of Risks in Work with Biological Agents
İÇİNDEKİLERIntroduction .......................................................................... 11Biological agents.................................................................. 12 Biology and molecular biology............................................ 21 Principles of biology and molecular biology........................ 22 Historical development of molecular biology ...................... 27 The cell: the smallest viable component of all life forms.................... 30 The bacterium Eschehchia coli: its chromosome, its plasmids.............................................. 33 The molecules of life: DNA, RNA, proteins............................................................ 35 The replication of DNA........................................................ 44 From DNA to protein: Mechanism of protein biosynthesis .................................... 45 Biotechnology ...................................................................... 53 Definition ............................................................................ 53 History and products .......................................................... 55 Modern (new) biotechnology .............................................. 59 Definition ............................................................................ 59 Fundamentals of genetic engineering ................................ 63 Spheres of application of modern biotechnology................ 69 Food production.............................................................. 69 Environment.................................................................... 69 Chemistry........................................................................ 70 Health.............................................................................. 70 Protein factors ............................................................ 71 Antihaemophilic Factor VIII ........................................ 74 Contribution of modern biotechnology to fundamental research .................................................... 77 Infection and defence against infection.............................. 78 Application of hybridoma technology ................................ 85 Monoclonal antibodies in diagnosis and therapy ................ 88 Safety plan for the handling of biological agents.............. 91 Further reading ....................................................................101 Glossary ................................................................................104 Index ......................................................................................117 ISSA publications ................................................................ 12 NOTLARMethods,Applications,Safety Considerations |
